Hermansky–Pudlak syndrome type 4 with interstitial pneumonia

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Hermansky–Pudlak syndrome type 4 with interstitial pneumonia

Hermansky-Pudlak syndrome (HPS) is an autosomal recessive disorder characterized by oculocutaneous albinism, bleeding tendency, and lysosomal accumulation of ceroid-like material, with occasional development of interstitial pneumonia (IP). Nine genetically distinct subtypes of HPS are known in humans; IP develops primarily in types 1 and 4. Most reported cases of HPS with IP are type 1, and the...

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ژورنال

عنوان ژورنال: Respiratory Medicine Case Reports

سال: 2013

ISSN: 2213-0071

DOI: 10.1016/j.rmcr.2013.04.002